Inflammation-suppressing cornea-in-a-syringe with anti-viral GF19 peptide promotes regeneration in HSV-1 infected rabbit corneas

Abstract Pathophysiologic inflammation, e.g., from HSV-1 viral infection, can cause tissue destruction resulting in ulceration, perforation, and ultimately blindness. We developed an injectable Cornea-in-a-Syringe (CIS) sealant-filler to treat damaged corneas. CIS comprises linear carboxylated polym...

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Hlavní autoři:	Egidijus Simoliunas, Inés Ruedas-Torres, Yolanda Jiménez-Gómez, Elle Edin, Mozhgan Aghajanzadeh-Kiyaseh, Mostafa Zamani-Roudbaraki, Rimvydas Asoklis, Milda Alksne, Neethi C. Thathapudi, Bijay K. Poudel, Ieva Rinkunaite, Kasparas Asoklis, Monika Iesmantaite, Laura Ortega-Llamas, Almantas Makselis, Marcelo Munoz, Daiva Baltriukiene, Virginija Bukelskiene, Jaime Gómez-Laguna, Miguel González-Andrades, May Griffith
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-03-01
Edice:	npj Regenerative Medicine
On-line přístup:	https://doi.org/10.1038/s41536-024-00355-1
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