From Stress to Survival: Trophoblast-Derived Extracellular Vesicle Proteome Captures Aspirin-Driven Cellular Reprogramming in a Preeclampsia Model

<b>Background:</b> Low-dose aspirin (LDA) reduces preeclampsia (PE) risk by up to 40%, yet its molecular effects on chorion trophoblast cells (CTCs), a fetal membrane lineage at the feto-maternal interface, remain obscure. CTCs form a structural and immunoregulatory barrier whose dysfunction drives...

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Autors principals:	Vineet Mahajan, Awanit Kumar, Jeena Jacob, Maged M. Costantine, Lauren S. Richardson, Rheanna Urrabaz-Garza, Emmanuel Amabebe, Ourlad Alzeus G. Tantengco, Ananth Kumar Kammala, Ramkumar Menon
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2026-05-01
Col·lecció:	Pharmaceutics
Matèries:	preeclampsia low-dose aspirin extracellular vesicles chorion trophoblast oxidative stress biomarkers
Accés en línia:	https://www.mdpi.com/1999-4923/18/6/677
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