Low-intensity pulsed ultrasound triggers a beneficial neuromodulation in dementia mice with chronic cerebral hypoperfusion via activation of hippocampal Fndc5/irisin signaling

Abstract Background Exercise-related signaling Fndc5/irisin expresses in brain and acts as a crucial regulator of cognitive function, but its detailed roles in vascular dementia (VaD) are still unclear. Low intensity pulsed ultrasound (LIPUS), a novel brain stimulation approach, has been suggested a...

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Detalhes bibliográficos

Principais autores:	Degang Song, Xiaomin Chen, Na Zhou, Yi Yuan, Shuo Geng, Cong Zhang, Zhe Zhao, Xingran Wang, Xinran Bao, Xifa Lan, Xiangjian Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-02-01
coleção:	Journal of Translational Medicine
Assuntos:	Fndc5/irisin LIPUS Dementia Hippocampus Chronic cerebral hypoperfusion Neurons
Acesso em linha:	https://doi.org/10.1186/s12967-022-03824-7
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