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Lipotype acquisition during neural development is not recapitulated in stem cell–derived neurons

We report a time-resolved resource of lipid molecule abundance across brain development. Using the resource as a reference, we find that stem cell–derived neurons do not acquire a neural lipotype in vitro, unless supplemented with adequate metabolic precursors. During development, different tissues...

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Principais autores: Anusha B Gopalan, Lisa van Uden, Richard R Sprenger, Nadine Fernandez-Novel Marx, Helle Bogetofte, Pierre A Neveu, Morten Meyer, Kyung-Min Noh, Alba Diz-Muñoz, Christer S Ejsing
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2024-05-01
coleção:Life Science Alliance
Acesso em linha:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202402622
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