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Higher protein kinase C ζ in fatty rat liver and its effect on insulin actions in primary hepatocytes.

We previously showed the impairment of insulin-regulated gene expression in the primary hepatocytes from Zucker fatty (ZF) rats, and its association with alterations of hepatic glucose and lipid metabolism. However, the molecular mechanism is unknown. A preliminary experiment shows that the expressi...

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Hlavní autoři: Wei Chen, Matthew Ray Goff, Heqian Kuang, Guoxun Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2015-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0121890
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