The IL-1β system in epilepsy-associated malformations of cortical development

Focal cortical dysplasia (FCD) and glioneuronal tumors (GNT) are recognized causes of chronic intractable epilepsy. The cellular mechanism(s) underlying their epileptogenicity remain largely unknown. Compelling evidence in experimental models of seizures indicates an important role of interleukin (I...

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Principais autores:	T. Ravizza, K. Boer, S. Redeker, W.G.M. Spliet, P.C. van Rijen, D. Troost, A. Vezzani, E. Aronica
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2006-10-01
Series:	Neurobiology of Disease
Assuntos:	Focal cortical dysplasia Glioneuronal tumors Astrocytes Microglia Dysmorphic neurons Pediatric epilepsy
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S0969996106001410
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