A diffusion model conditioned on compound bioactivity profiles for generating high-content images

Abstract High-content imaging (HCI) provides a rich snapshot of compound-induced phenotypic outcomes that augment our understanding of how compounds affect cellular systems. Generative imaging models for HCI provide a route towards anticipating the phenotypic outcomes of chemical perturbations in si...

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Bibliografiske detaljer

Principais autores:	Steven Cook, Jason Chyba, Laura Gresoro, Doug Quackenbush, Minhua Qiu, Peter Kutchukian, Eric J. Martin, Peter Skewes-Cox, William J. Godinez
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2026-04-01
Serier:	Scientific Reports
Fag:	Generative AI for drug discovery In silico HCI Virtual screening
Online adgang:	https://doi.org/10.1038/s41598-026-44976-6
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