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Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial

Background:. Primary sclerosing cholangitis is a progressive inflammatory liver disease characterized by biliary and liver fibrosis. Vascular adhesion protein-1 (VAP-1) is important in the inflammatory process driving liver fibrosis. We evaluated the safety and efficacy of VAP-1 blockade with a mono...

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Principais autores: Gideon M. Hirschfield, Katherine Arndtz, Amanda Kirkham, Yung-Yi Chen, Richard Fox, Anna Rowe, Jessica Douglas-Pugh, Douglas Thorburn, Eleanor Barnes, Guruprasad P. Aithal, Diana Hull, Khushpreet Bhandal, Kathryn Olsen, Paul Woodward, Siân Lax, Philip Newsome, David J. Smith, Antero Kallio, David H. Adams, Victoria Homer, Chris J. Weston
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Health/LWW 2024-05-01
Serier:Hepatology Communications
Online adgang:http://journals.lww.com/10.1097/HC9.0000000000000426
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