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Comparative assessment of SNP genotyping assays for challenging forensic samples utilizing ancient DNA methods

Abstract Background The fields of ancient DNA research and forensic genetics share both methodological similarities and common challenges, particularly in the analysis of degraded DNA. Leveraging these overlaps, this study evaluates three single nucleotide polymorphisms (SNP)-based genotyping assays...

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Principais autores: Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling, Siri Aili Fagerholm, Ricky Ansell, Anders Götherström, Andreas Tillmar
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:Genome Biology
Fag:
Forensic genetics
Ancient DNA
Degraded DNA
Forensic investigative genetic genealogy
SNP
Bone
Online adgang:https://doi.org/10.1186/s13059-025-03912-z
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