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Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum.

Inflammasome is an intracellular protein complex that serves as cytosolic pattern recognition receptor (PRR) to engage with pathogens and to process cytokines of the interleukin-1 (IL-1) family into bioactive molecules. It has been established that interleukin-1β (IL-1β) is important to host defense...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Principais autores: Tzu-Hsuan Chang, Juin-Hua Huang, Hsiu-Chao Lin, Wen-Yu Chen, Yu-Hsiang Lee, Li-Chung Hsu, Mihai G Netea, Jenny P-Y Ting, Betty A Wu-Hsieh
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2017-07-01
סדרה:PLoS Pathogens
גישה מקוונת:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006485&type=printable
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