A novel homoarginine-containing cyclic peptide pioamide with selective antipseudomonal activity isolated from the nematode symbiont Photorhabdus khanii

ABSTRACT Gram-negative bacteria harbor an outer membrane that physically protects them from the penetration of antibiotics into the cells. This barrier makes it challenging to develop antibiotics that effectively kill Gram-negative pathogens. The entomopathogenic bacterium Photorhabdus species produ...

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Principais autores:	Yu Imai, Sangkeun Son, Miho Sasaki, Libang Liang, Michael F. Gates, Meghan Ghiglieri, Takeshi Shimosato, Chandrashekhar Honrao, Xiaoyu Ma, Jason J. Guo, Kim Lewis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2025-10-01
coleção:	Applied and Environmental Microbiology
Assuntos:	Pseudomonas aeruginosa nematode symbionts Photorhabdus antibiotic
Acesso em linha:	https://journals.asm.org/doi/10.1128/aem.01123-25
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