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Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients

<p>Abstract</p> <p>Background</p> <p>End-stage renal disease (ESRD) patients treated with renal replacement therapy (RRT) have premature immunologically aged T cells which may underlie uremia-associated immune dysfunction. The aim of this study was to investigate whether uremia was able to induce pr...

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Hoofdauteurs: Meijers Ruud WJ, Litjens Nicolle HR, de Wit Elly A, Langerak Anton W, van der Spek Ashley, Baan Carla C, Weimar Willem, Betjes Michiel GH
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2012-09-01
Reeks:Immunity & Ageing
Onderwerpen:
Ageing
CD28null
End-stage renal disease
Renal replacement therapy
T lymphocytes
Uremia
Online toegang:http://www.immunityageing.com/content/9/1/19
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