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The Role of the Prader-Willi Syndrome Critical Interval for Epigenetic Regulation, Transcription and Phenotype

Prader-Willi Syndrome (PWS) is a neurodevelopmental disorder caused by loss of expression of the paternally inherited genes on chromosome 15q11.2-q13. However, the core features of PWS have been attributed to a critical interval (PWS-cr) within the 15q11.2-q13 imprinted gene cluster, containing the...

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Autors principals: Simona Zahova, Anthony R. Isles
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2018-10-01
Col·lecció:Epigenomes
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Accés en línia:http://www.mdpi.com/2075-4655/2/4/18
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