Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

Abstract Background Radiotherapy has been used increasingly to treat primary hepatocellular carcinoma. Clinically, the main cause of radiotherapy failure is cellular radioresistance, conferred via glycolytic metabolism. Our previous study demonstrated that Girdin is upregulated in primary hepatocell...

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Auteurs principaux:	Li Yu, Yifan Sun, Jingjing Li, Yan Wang, Yuxing Zhu, Yong Shi, Xiaojun Fan, Jianda Zhou, Ying Bao, Jie Xiao, Ke Cao, Peiguo Cao
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2017-08-01
Collection:	Journal of Experimental & Clinical Cancer Research
Sujets:	Girdin Primary hepatocellular carcinoma Glycolysis Radio-sensitivity
Accès en ligne:	http://link.springer.com/article/10.1186/s13046-017-0580-7
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