In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning

The in vivo detection of dead cells remains a major challenge due to technical hurdles. Here, we present a novel method, where injection of fluorescent milk fat globule-EGF factor 8 protein (MFG-E8) in vivo combined with imaging flow cytometry and deep learning allows the identification of dead cell...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Jan Kranich, Nikolaos-Kosmas Chlis, Lisa Rausch, Ashretha Latha, Martina Schifferer, Tilman Kurz, Agnieszka Foltyn-Arfa Kia, Mikael Simons, Fabian J. Theis, Thomas Brocker
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2020-01-01
Schriftenreihe:	Journal of Extracellular Vesicles
Schlagworte:	extracellular vesicles exosomes dendritic cells viral infection irradiation apoptosis
Online-Zugang:	http://dx.doi.org/10.1080/20013078.2020.1792683
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