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Clinical experience with a novel assay measuring cytomegalovirus (CMV)-specific CD4+ and CD8+ T-cell immunity by flow cytometry and intracellular cytokine staining to predict clinically significant CMV events

Abstract Background Cytomegalovirus (CMV) infection is one of the most common opportunistic infections following organ transplantation, despite administration of CMV prophylaxis. CMV-specific T-cell immunity (TCI) has been associated with reduced rates of CMV infection. We describe for the first tim...

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Principais autores: Ralph Rogers, Kapil Saharia, Aditya Chandorkar, Zoe F. Weiss, Kendra Vieira, Sophia Koo, Dimitrios Farmakiotis
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-01-01
Serier:BMC Infectious Diseases
Fag:
CMV
Cytomegalovirus
Transplantation
Immunoassays
(val)ganciclovir
Online adgang:https://doi.org/10.1186/s12879-020-4787-4
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