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Attenuation of PM2.5-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion

Abstract Background Exposure to particulate matter (PM) with an aerodynamic diameter less than 2.5 μm (PM2.5) is a risk factor for developing pulmonary diseases and the worsening of ongoing disease. Mitochondrial fission and fusion are essential processes underlying mitochondrial homeostasis in heal...

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Principais autores: Qi Liu, Jiali Weng, Chenfei Li, Yi Feng, Meiqin Xie, Xiaohui Wang, Qing Chang, Mengnan Li, Kian Fan Chung, Ian M Adcock, Yan Huang, Hai Zhang, Feng Li
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-07-01
Serier:Particle and Fibre Toxicology
Fag:
Mitochondrial fission
Mitochondrial fusion
PM2.5
Mitophagy
Mitochondrial oxygen consumption rate (OCR)
Mitochondrial morphology
Online adgang:https://doi.org/10.1186/s12989-023-00534-w
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