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Development of Recombinant PLC-Zeta Protein as a Therapeutic Intervention for the Clinical Treatment of Oocyte Activation Failure

The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca<sup>2+</sup> release responsible for oocyte activation during mammalian fertilization. The increasing number of genetic and clinical reports that directly link...

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Principais autores: Alaaeldin Saleh, Angelos Thanassoulas, Elnur Aliyev, Karl Swann, Azza Naija, Huseyin C. Yalcin, F. Anthony Lai, Michail Nomikos
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-05-01
Serier:Biomedicines
Fag:
male infertility
phospholipase C
PLC-zeta
sperm
IVF
ICSI
Online adgang:https://www.mdpi.com/2227-9059/12/6/1183
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