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PF-04691502, a PI3K/mTOR Dual Inhibitor, Ameliorates AD-like Pathology in a Mouse Model of AD

Alzheimer’s disease (AD) is a neurodegenerative disorder that significantly impacts the lives of patients and their families. The pathological features of AD include the accumulation of amyloid-β (Aβ) and Tau, which disrupt neuronal function and communication, ultimately leading to neuronal loss and...

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Bibliografische Detailangaben
Hauptverfasser: Marika Lanza, Rossella Basilotta, Antonella Caccamo, Giovanna Casili, Alberto Repici, Salvatore Oddo, Emanuela Esposito
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2025-09-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/14/18/1474
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