POU2F2 as a dual oncogenic and immunomodulatory driver in kidney renal clear cell carcinoma
Kidney renal clear cell carcinoma (KIRC) features an immunosuppressive tumor microenvironment (TME). We investigated the role of transcription factor POU2F2 in KIRC oncogenesis and macrophage polarization. Single-cell and spatial transcriptomics showed that POU2F2 is upregulated in KIRC and associat...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis Group
2026-12-01
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| Serija: | Cell Adhesion & Migration |
| Teme: | |
| Online pristup: | https://www.tandfonline.com/doi/10.1080/19336918.2026.2700062 |
| Oznake: |
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