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Tumor-induced osteomalacia

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome clinically characterized by bone pain, fractures and muscle weakness. It is caused by tumoral overproduction of fibroblast growth factor 23 (FGF23) that acts primarily at the proximal renal tubule, decreasing phosphate reabsorption a...

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Bibliografiske detaljer
Principais autores: Pablo Florenzano, Rachel I. Gafni, Michael T. Collins
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017-12-01
Serier:Bone Reports
Fag:
Online adgang:http://www.sciencedirect.com/science/article/pii/S235218721730027X
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