High-dose melphalan-based chemotherapy and autologous stem-cell transplantation for high-risk osteosarcoma in children: A single-institute experience and review of the literature

Background: The prognosis of high-risk osteosarcoma, defined by the presence of chemo-resistance, metastatic disease at diagnosis, and relapse, remains poor. The efficacy of high-dose chemotherapy (HDC) and autologous stem-cell transplantation (ASCT) for high-risk osteosarcoma is still unclear. Meth...

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Principais autores:	Hideki Sakiyama, Satoru Hamada, Nobuyuki Hyakuna, Takeshi Yagi, Tokiko Oshiro, Taichi Uehara, Shinobu Kiyuna, Jiro Miyamoto, Takehiro Matsuda, Takeshi Higa, Koichi Nakanishi
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2021-12-01
סדרה:	Pediatric Hematology Oncology Journal
נושאים:	Autologous stem-cell transplantation High-dose chemotherapy Melphalan Osteosarcoma
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2468124521002473
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