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Mechanism of DUX-induced differentiation of mESC into extraembryonic endoderm

Objective·To explore the effect of double homeobox (DUX) protein on the differentiation potential of mouse embryonic stem cells (mESCs) into extraembryonic endoderm (XEN) and the possible mechanism of its action.Methods·Overexpression of DUX cell lines in mESCs was achieved by using a lentiviral sys...

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Principais autores: HONG Lei, GUO Chuanliang, CAI Qin, LI Wanrui, ZENG Yitao, XUE Yan, ZENG Fanyi
格式: Artigo
語言:Chinês
出版: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2024-11-01
叢編:Shanghai Jiaotong Daxue xuebao. Yixue ban
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在線閱讀:https://xuebao.shsmu.edu.cn/article/2024/1674-8115/1674-8115-2024-44-11-1359.shtml
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