Synthesis and Antiproliferative Activity of Thiazolyl-bis-pyrrolo[2,3-b]pyridines and Indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, Nortopsentin Analogues

Two new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and indole units were both substituted by 7-azaindole moieties or one indole unit was replaced by a 6-azaindole portion, were efficiently synthesized. Compounds belonging to both se...

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Detalhes bibliográficos

Principais autores:	Anna Carbone, Barbara Parrino, Gloria Di Vita, Alessandro Attanzio, Virginia Spanò, Alessandra Montalbano, Paola Barraja, Luisa Tesoriere, Maria Antonia Livrea, Patrizia Diana, Girolamo Cirrincione
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2015-01-01
coleção:	Marine Drugs
Assuntos:	marine alkaloids bis-indolyl alkaloids nortopsentins thiazolyl-bis-pyrrolo [2,3-b]pyridines indolyl-thiazolyl-pyrrolo[2,3-c]pyridines apoptosis autophagic death antiproliferative activity
Acesso em linha:	http://www.mdpi.com/1660-3397/13/1/460
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