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The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

Proper regulation of neurogenesis, the process by which new neurons are generated from neural stem and progenitor cells (NS/PCs), is essential for embryonic brain development and adult brain function. The transcription regulator Patz1 is ubiquitously expressed in early mouse embryos and has a key ro...

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Principais autores: Sara Mancinelli, Michela Vitiello, Maria Donnini, Francesca Mantile, Giuseppe Palma, Antonio Luciano, Claudio Arra, Laura Cerchia, Giovanna Lucia Liguori, Monica Fedele
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-04-01
coleção:Frontiers in Cell and Developmental Biology
Assuntos:
neurogenesis
neural stem cells
PATZ1
knockout mice
neurosphere assay
subventricular zone
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcell.2021.657149/full
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