Identification and validation of Birc5 as a novel activated cell cycle program biomarker associated with infiltration of immunosuppressive myeloid‐derived suppressor cells in hepatocellular carcinoma

Abstract Background Preclinical studies and clinical trials have demonstrated that tumor‐intrinsic activation of the cell cycle program impedes anticancer immunotherapy. Identification of cell cycle‐related biomarkers may provide novel therapeutic targets to augment the efficacy of immunotherapy in...

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Hlavní autoři:	Yun Liu, Xi Chen, Wenwu Luo, Yufei Zhao, Björn Nashan, Lei Huang, Xiaodong Yuan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2023-08-01
Edice:	Cancer Medicine
Témata:	Birc5 cell cycle hepatocellular carcinoma (HCC) immunotherapy myeloid‐derived suppressor cells (MDSCs) tumor microenvironment
On-line přístup:	https://doi.org/10.1002/cam4.6271
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