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Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A

The metastasis suppressor protein NME1 is an evolutionarily conserved and multifunctional enzyme that plays an important role in suppressing the invasion and metastasis of tumour cells. The nucleoside diphosphate kinase (NDPK) activity of NME1 is well recognized in balancing the intracellular pools...

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Principais autores: Bess Yi Kun Yu, Maria-Armineh Tossounian, Stefan Denchev Hristov, Ryan Lawrence, Pallavi Arora, Yugo Tsuchiya, Sew Yeu Peak-Chew, Valeriy Filonenko, Sally Oxenford, Richard Angell, Jerome Gouge, Mark Skehel, Ivan Gout
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-08-01
Colecção:Redox Biology
Assuntos:
NDPK
Coenzyme A
Protein CoAlation
Oxidative stress
Metastasis suppressor
Redox regulation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2213231721001269
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