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Clinical and cost-effectiveness of lithium versus quetiapine augmentation for treatment-resistant depression in adults: LQD a pragmatic randomised controlled trial

Background Lithium and several atypical antipsychotics are the recommended first-line augmentation options for treatment-resistant depression; however, few studies have compared them directly, and none for longer than 8 weeks. Consequently, there is little evidence-based guidance for clinicians when...

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Principais autores: Jess Kerr-Gaffney, Zohra Zenasni, Kimberley Goldsmith, Nahel Yaziji, Huajie Jin, Alessandro Colasanti, John Geddes, David Kessler, R Hamish McAllister-Williams, Allan H Young, Alvaro Barrera, Lindsey Marwood, Rachael W Taylor, Helena Tee, Anthony J Cleare
Format: Artigo
Sprog:Inglês
Udgivet: NIHR Journals Library 2025-05-01
Serier:Health Technology Assessment
Fag:
depression
depressive disorder
major
antidepressive agents
lithium
quetiapine fumarate
antipsychotic agents
randomised controlled trial
Online adgang:https://doi.org/10.3310/YQVF5347
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