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Activation of c-Jun by human cytomegalovirus UL42 through JNK activation.

c-Jun is a major component of the AP-1 transactivator complex. In this report, we demonstrated that AP-1 was activated by the expression of UL42, a human cytomegalovirus-encoded membrane protein that has two PPXY (PY) motifs and a C-terminal transmembrane domain (TMD). Although UL42 interacts with I...

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Váldodahkkit: Tetsuo Koshizuka, Naoki Inoue
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2020-01-01
Ráidu:PLoS ONE
Liŋkkat:https://doi.org/10.1371/journal.pone.0232635
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