The RNA m6A writer METTL3 in tumor microenvironment: emerging roles and therapeutic implications

The tumor microenvironment (TME) is a heterogeneous ecosystem comprising cancer cells, immune cells, stromal cells, and various non-cellular components, all of which play critical roles in controlling tumor progression and response to immunotherapies. Methyltransferase-like 3 (METTL3), the core comp...

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Autores principales:	Weiqi Su, Lin Che, Wenting Liao, Huilin Huang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2024-01-01
Colección:	Frontiers in Immunology
Materias:	methyltransferase-like 3 (METTL3) N6-methyladenosine (m6A) tumor-infiltrating immune cells (TICs) small molecular inhibitors cancer immunotherapy immune checkpoint inhibitors (ICI)
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1335774/full
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