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GOLPH3 promotes calcium oxalate-induced renal injury and fibrosis through Golgi stress-mediated apoptosis and inflammatory responses

Abstract A common urological disorder, calcium oxalate (CaOx) stones are the most common form of kidney stones. Deposition of CaOx crystals leads to tubular damage, interstitial fibrosis, and chronic kidney disease. Understanding the intrinsic mechanisms of kidney stone formation is essential for th...

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Bibliografische Detailangaben
Hauptverfasser: Bao-feng Song, Bo-jun Li, Yushi Sun, Ming Li, Ting Rao, Yuan Ruan, Fan Cheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-03-01
Schriftenreihe:Scientific Reports
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Online-Zugang:https://doi.org/10.1038/s41598-025-91638-0
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