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Neonatal overfeeding induced glucocorticoid overexposure accelerates hepatic lipogenesis in male rats

Abstract Background Postnatal overfeeding activates tissue glucocorticoid (GC) activity by up-regulating 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) and increasing sensitivity to high-fat (HF) diet-induced non-alcoholic fatty liver disease (NAFLD). The present study aimed to evaluate the effects o...

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Huvudupphov: Fan Yang, Yanyan Dai, Cuiting Min, Xiaonan Li
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2018-05-01
Serie:Nutrition & Metabolism
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Länkar:http://link.springer.com/article/10.1186/s12986-018-0272-0
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