Maternal hyperglycemia induces alterations in hepatic amino acid, glucose and lipid metabolism of neonatal offspring: Multi-omics insights from a diabetic pig model

Objective: To gain mechanistic insights into adverse effects of maternal hyperglycemia on the liver of neonates, we performed a multi-omics analysis of liver tissue from piglets developed in genetically diabetic (mutant INS gene induced diabetes of youth; MIDY) or wild-type (WT) pigs. Methods: Prote...

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Egile Nagusiak:	Bachuki Shashikadze, Libera Valla, Salvo Danilo Lombardo, Cornelia Prehn, Mark Haid, Fabien Riols, Jan Bernd Stöckl, Radwa Elkhateib, Simone Renner, Birgit Rathkolb, Jörg Menche, Martin Hrabĕ de Angelis, Eckhard Wolf, Elisabeth Kemter, Thomas Fröhlich
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2023-09-01
Saila:	Molecular Metabolism
Gaiak:	Maternal diabetes Neonates Liver Pig model Proteomics Metabolomics
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S2212877823001023
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