Mutations in <italic toggle="yes">hmg1</italic>, Challenging the Paradigm of Clinical Triazole Resistance in <named-content content-type="genus-species">Aspergillus fumigatus</named-content>

ABSTRACT Aspergillus fumigatus is the predominant pathogen of invasive aspergillosis, a disease state credited with over 200,000 life-threatening infections each year. The triazole class of antifungals are clinically essential to the treatment of invasive aspergillosis, both as frontline and as salv...

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Detalhes bibliográficos

Principais autores:	Jeffrey M. Rybak, Wenbo Ge, Nathan P. Wiederhold, Josie E. Parker, Steven L. Kelly, P. David Rogers, Jarrod R. Fortwendel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2019-04-01
coleção:	mBio
Assuntos:	Aspergillus fumigatus HMG-CoA reductase antifungal resistance ergosterol hmg1 triazole
Acesso em linha:	https://journals.asm.org/doi/10.1128/mBio.00437-19
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