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Identification and characterization of naturally occurring splice variants of SAMHD1

<p>Abstract</p> <p>Background</p> <p>Sterile Alpha Motif and HD domain-containing protein 1 (SAMHD1) is a recently identified host factor that restricts HIV-1 replication in dendritic and myeloid cells. SAMHD1 is a dNTPase that presumably reduces the cellular dNTP levels to levels too low for retrov...

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Bibliographic Details
Main Authors: Welbourn Sarah, Miyagi Eri, White Tommy E, Diaz-Griffero Felipe, Strebel Klaus
Format: Artigo
Language:Inglês
Published: BMC 2012-10-01
Series:Retrovirology
Subjects:
Online Access:http://www.retrovirology.com/content/9/1/86
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