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Telomere-related DNA damage response pathways in cancer therapy: prospective targets

Maintaining the structural integrity of genomic chromosomal DNA is an essential role of cellular life and requires two important biological mechanisms: the DNA damage response (DDR) mechanism and telomere protection mechanism at chromosome ends. Because abnormalities in telomeres and cellular DDR re...

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Auteurs principaux: Liting Gu, Mingdi Liu, Yuning Zhang, Honglan Zhou, Yishu Wang, Zhi-Xiang Xu
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2024-06-01
Collection:Frontiers in Pharmacology
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Accès en ligne:https://www.frontiersin.org/articles/10.3389/fphar.2024.1379166/full
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