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397 Harnessing the potential of genetic compensation in amyotrophic lateral sclerosis

Objectives/Goals: This study aims to explore transcriptional adaptation, where mutations in one gene trigger compensatory changes in related genes, and how this affects the variability in clinical manifestations of amyotrophic lateral sclerosis (ALS). Methods/Study Population: The presence of a prem...

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Autori principali: Adriana Morales Gomez, Nathan Staff, Stephen C. Ekker
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cambridge University Press 2026-04-01
Serie:Journal of Clinical and Translational Science
Accesso online:https://www.cambridge.org/core/product/identifier/S2059866126105561/type/journal_article
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