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The effect of host factors on discriminatory performance of a transcriptomic signature of tuberculosis risk

Summary: Background: We aimed to understand host factors that affect discriminatory performance of a transcriptomic signature of tuberculosis risk (RISK11). Methods: HIV-negative adults aged 18–60 years were evaluated in a prospective study of RISK11 and surveilled for tuberculosis through 15 month...

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Principais autores: Humphrey Mulenga, Andrew Fiore-Gartland, Simon C. Mendelsohn, Adam Penn-Nicholson, Stanley Kimbung Mbandi, Bhavesh Borate, Munyaradzi Musvosvi, Michèle Tameris, Gerhard Walzl, Kogieleum Naidoo, Gavin Churchyard, Thomas J. Scriba, Mark Hatherill
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-03-01
coleção:EBioMedicine
Assuntos:
Mycobacterium tuberculosis
Transcriptomic
Signature
RNA
Host factors
Performance
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396422000706
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