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A case of sequential medical therapy for advanced ureteral cancer in Li–Fraumeni syndrome

Introduction Li–Fraumeni syndrome, an autosomal dominant cancer predisposition syndrome caused by a pathogenic variant of TP53, a tumor suppressor gene, leads to a high risk from early childhood of developing various types of cancers. Here, we report a case of advanced ureteral cancer in Li–Fraumeni...

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Principais autores: Minami Une, Ryo Fujiwara, Arisa Ueki, Ryosuke Oki, Tetsuya Urasaki, Kentaro Inamura, Shunji Takahashi, Junji Yonese, Takeshi Yuasa
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2023-09-01
coleção:IJU Case Reports
Assuntos:
advanced urothelial cancer
avelumab
immune checkpoint inhibitor
Li–Fraumeni syndrome
TP53 pathogenic variant
Acesso em linha:https://doi.org/10.1002/iju5.12607
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