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DNA methylation in adaptation to high-altitude environments and pathogenesis of related diseases

Abstract High-altitude environments, characterized by hypoxia, low temperatures, and intense ultraviolet radiation, pose significant challenges to human physiology and health. DNA methylation, as a key epigenetic regulatory mechanism, plays a central role in human adaptation to high-altitude environ...

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Principais autores: Xingkai Zhang, Yuxi Yang, Qinghai Shi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-08-01
Serier:Human Genomics
Fag:
High-altitude
Adaptation
Diseases
DNA methylation
Epigenetic
Hypoxia
Online adgang:https://doi.org/10.1186/s40246-025-00794-x
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