Shuangshen granules enhance anti-PD1 therapy effectiveness in lung adenocarcinoma by modulating myeloid-derived suppressor cell-induced T cell exhaustion

Abstract Background Worldwide, lung cancer is the most common cause of cancer-related deaths. Molecular targeted therapies and immunotherapies for non-small-cell lung cancer (NSCLC) have improved outcomes markedly over the past two decades. However, the vast majority of advanced NSCLCs become resist...

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Prif Awduron:	Zhong-ning He, Qi Huang, Yi Li, Jia-qi Hu, Tong-tong Liu, Yu-wei Zhao, Xiao-ling Ren, Shu-lin He, Yue Li, Bo-lun Shi, Rui Liu, Qiu-jun Guo, Xing Zhang, Zhan Shi, Jie He, Run-zhi Qi, Bao-jin Hua
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2026-05-01
Cyfres:	Chinese Medicine
Pynciau:	Shuangshen granules Lung adenocarcinoma Myeloid-derived suppressor cells Immunotherapy T cell exhaustion
Mynediad Ar-lein:	https://doi.org/10.1186/s13020-026-01391-3
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