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PCB 153 Modulates Genes Involved in Proteasome and Neurodegeneration-Related Pathways in Differentiated SH-SY5Y Cells: A Transcriptomic Study

Polychlorinated biphenyls (PCBs) are persistent environmental contaminants associated with neurotoxicity and increased risk of neurodegenerative diseases. PCB 153, a highly abundant non-coplanar congener, bioaccumulates in human tissues and impairs homeostasis. This study investigated the transcript...

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Principais autores: Aurelio Minuti, Serena Silvestro, Claudia Muscarà, Michele Scuruchi, Simone D’Angiolini
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2026-01-01
coleção:Cells
Assuntos:
polychlorinated biphenyls
neurotoxicity mechanisms
environmental pollutants
PCB 153
exposure assessment
risk characterization
Acesso em linha:https://www.mdpi.com/2073-4409/15/3/217
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