Investigating the shared genetic architecture between primary sclerosing cholangitis and inflammatory bowel diseases: a Mendelian randomization study

Abstract Background Several studies have found that primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD) are closely associated. However, the direction and causality of their interactions remain unclear. Thus, this study employs Mendelian Randomization to explore whether there a...

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Hauptverfasser:	Xuan Dong, Li-Li Gong, Mei-Zhu Hong, Jin-Shui Pan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-02-01
Schriftenreihe:	BMC Gastroenterology
Schlagworte:	Mendelian randomization Primary sclerosing cholangitis Ulcerative colitis Crohn’s disease
Online-Zugang:	https://doi.org/10.1186/s12876-024-03162-6
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