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Advancements Exploring Major Depressive Disorder: Insights on Oxidative Stress, Serotonin Metabolism, BDNF, HPA Axis Dysfunction, and Pharmacotherapy Advances

Major depressive disorder (MDD), a prevalent mental illness, is marked by a complex mixture of biological factors. This review focuses on the roles of oxidative stress, tryptophan-serotonin metabolism, brain-derived neurotrophic factor (BDNF), and the hypothalamic–pituitary–adrenal (HPA) axis in MDD...

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Principais autores: Ana Salomé Correia, Nuno Vale
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-03-01
Serier:International Journal of Translational Medicine
Fag:
major depressive disorder
oxidative stress
tryptophan
serotonin
brain-derived neurotrophic factor
hypothalamic–pituitary–adrenal axis
Online adgang:https://www.mdpi.com/2673-8937/4/1/10
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