Combined assessment of stromal tumor infiltrating lymphocytes and tumor peroxiredoxin 4 expression improved prognostic stratification in postoperative pancreatic cancer patients

Abstract Background Pancreatic cancer (PC) is characterized by profound immunosuppression and marked biological heterogeneity. Stromal tumor-infiltrating lymphocytes (TILs) reflect host antitumor immunity, whereas peroxiredoxin 4 (PRDX4) represents tumor redox adaptation. However, their combined pro...

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Detalhes bibliográficos

Principais autores:	Yao Liu, Jia Han, Akihiro Shioya, Wenpeng Jiao, Masashi Okuro, Tohru Ito, Sohsuke Yamada
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	Diagnostic Pathology
Assuntos:	Pancreatic cancer (PC) Tumor-infiltrating lymphocytes (TILs) Peroxiredoxin 4 (PRDX4) Tumor microenvironment Redox regulation Prognosis
Acesso em linha:	https://doi.org/10.1186/s13000-026-01786-8
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