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Tumor Treating Fields Alter the Kinomic Landscape in Glioblastoma Revealing Therapeutic Vulnerabilities

Treatment for the deadly brain tumor glioblastoma (GBM) has been improved through the non-invasive addition of alternating electric fields, called tumor treating fields (TTFields). Improving both progression-free and overall survival, TTFields are currently approved for treatment of recurrent GBMs a...

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Main Authors: Amber B. Jones, Taylor L. Schanel, Mikayla R. Rigsby, Corinne E. Griguer, Braden C. McFarland, Joshua C. Anderson, Christopher D. Willey, Anita B. Hjelmeland
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
glioblastoma
tumor treating fields
temozolomide resistance
kinomics
Online Access:https://www.mdpi.com/2073-4409/12/17/2171
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