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Bacterial biofilm-derived H-NS protein acts as a defense against Neutrophil Extracellular Traps (NETs)

Abstract Extracellular DNA (eDNA) is crucial for the structural integrity of bacterial biofilms as they undergo transformation from B-DNA to Z-DNA as the biofilm matures. This transition to Z-DNA increases biofilm rigidity and prevents binding by canonical B-DNA-binding proteins, including nucleases...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: AL Hendricks, KR More, A. Devaraj, JR Buzzo, FH Robledo-Avila, S. Partida-Sanchez, LO Bakaletz, SD Goodman
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Portfolio 2025-04-01
Cyfres:npj Biofilms and Microbiomes
Mynediad Ar-lein:https://doi.org/10.1038/s41522-025-00691-0
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