Epigenetic mechanisms leading to overexpression of HMGA proteins in human pituitary adenomas
Overexpression of the HMGA1 and HMGA2 proteins is a feature of all human pituitary adenoma subtypes. However, amplification and/or rearrangement of the HMGA2 have been described in human prolactinomas, but rarely in other pituitary subtypes, and no genomic amplification of HMGA1 was detected in pitu...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015-06-01
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| coleção: | Frontiers in Medicine |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00039/full |
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