Arf4 is required for Mammalian development but dispensable for ciliary assembly.
The primary cilium is a sensory organelle, defects in which cause a wide range of human diseases including retinal degeneration, polycystic kidney disease and birth defects. The sensory functions of cilia require specific receptors to be targeted to the ciliary subdomain of the plasma membrane. Arf4...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2014-02-01
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| Serija: | PLoS Genetics |
| Online dostop: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004170&type=printable |
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