The projection from the prelimbic cortex to the ventral tegmental area negatively regulates 5-HT-induced itch-scratching and positively regulates itch-related aversion in rats

Direct and indirect evidence suggests that the prelimbic cortex (PrL) and the ventral tegmental area (VTA) are the key brain regions involved in the regulation of itch sensation and itch-related emotions. The PrL projects widely to various cortical and subcortical brain regions, with the VTA being o...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Xing-Yu Lu, Jun-Fei Teng, Juan Yao, Xuan Li, Bing Wu, Xue-Qiang Hu, Ping Wang, Xiao-Qian Jiang, Jian-Feng Sui, Ke-Hui Hu, Yue-Ming Xu, Shu-Lei Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-04-01
Schriftenreihe:	Brain Research Bulletin
Schlagworte:	Itch Prelimbic cortex Ventral tegmental area Aversion
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0361923025000954
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